Anti-Parasite & Anti-Protozoa

Link to PubMed Peer-Reviewed Articles

 

PubMed Anti-Parasite  According to the CDC (Center for Communicable Diseases), Parasitic infections cause a tremendous burden of disease in both the tropics and subtropics as well as in more temperate climates. Of all parasitic diseases, malaria causes the most deaths globally. Malaria kills approximately 660,000 people each year, most of them young children in sub-Saharan Africa.

The Neglected Tropical Diseases (NTDs), which have suffered from a lack of attention by the public health community, include parasitic diseases such as lymphatic filariasis, onchocerciasis, and Guinea worm disease. The NTDs affect more than 1 billion people—one-sixth of the world’s population—largely in rural areas of low-income countries. These diseases extract a large toll on endemic populations, including lost ability to attend school or work, retardation of growth in children, impairment of cognitive skills and development in young children, and the serious economic burden placed on entire countries.

A past article by some noted PDT experts  "Photodynamic antimicrobial chemotherapy (PACT) for the treatment of malaria, leishmaniasis and trypanosomiasis" stated the following:

"In terms of healing properties, the application of photosensitizers to TD (tropical diseases) is likely to be of greatest utility where there is either a skin or a soft tissue manifestation of the disease. Because photodynamic antimicrobial chemotherapy (PACT) is dependent upon exposure to a directed light source, it allows local treatment and control, but consequently cannot affect advanced, disseminated diseases  Conversely, no microorganism resistance has been reported against PACT, and the low cost of commonly available photosensitizers, coupled with the availability of inexpensive low-power light sources, suggests that this approach is of great potential healthcare benefit in TD .  The potential use of PACT to kill parasites and control TD has not yet been even moderately exploited.

*Note the above belief that PACT can only be a local, superficial therapy is outdated with the introduction of SPDT and deep body treatments.  We look forward to studies using this advance technology for malaria, leishmaniasis, trypanosomiasis and a host of other protozoal diseases..

 

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Leishmaniasis Lesions before

After Photodynamic Therapy